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Sampangine-based fungicides
 


The naturally occurring compound, called Sampangine was first patented in the USA as a treatment for human fungal infections but it was never released pharmaceutically.

ARS plant pathologist David Wedge and associate professor Dale Nagle of the University of Mississippi have patented this same substance and other related compounds as broad-spectrum, low toxicity fungicides for use in agriculture and horticulture.

Sampangine based compounds have been found to control Botrytis cinerea. This is especially important since some strains of Botrytis resist commonly used fungicides. Sampangine also controls Colletotrichum fragariae that causes crown rot and wilt in strawberry plants; C. gloeosporioides that attacks numerous plants including grapes, strawberry, citrus and papaya and Fusarium oxysporum that induces vascular wilt.

Sampangine based fungicides may also find use as post-harvest and preserving agents. Contact the ARS for further information: www.ars.usda.gov